Don’t clutter up your arrangement with a bunch of unnecessary crap. Spend more time adjusting, tweaking and coaxing the elements in your sounds and arrangement, less time tweaking your mix. Get your sounds working. Don’t be afraid to automation if you need to, even if it’s just the filter cutoff, It’s more interesting that way. If something is just not cutting through, maybe try changing the sound or instrument entirely. If your sample isn’t cutting it, find a new one. If your lacking in samples there’s so many high quality, amazing sample sets available today. Try looking at Beatport’s Sounds To Sample.